Stem cells for neurogenesis?...
Washington April 30, 2004 11:40:07 AM IST
A preliminary study conducted at the University of Florida Shands Cancer Center, USA, suggests that transplanted adult bone-marrow cells could regenerate nerve cells in the brains of human stem-cell recipients.
The findings published in The Lancet, if confirmed in future research, could have implications for the treatment of neurodegenerative disorders such as Parkinson's disease.
Edward Scott and colleagues examined the brain tissue of three women who had received bone-marrow transplantation from male donors to help treat leukaemia.
The investigators found that donor cells containing a Y chromosome (ie, from a male origin) were present in all three women's brains up to 6 years after bone-marrow transplantation. All recipients had transgender brain tissue, and in the longest survivor three different types of brain tissue including neurons were found.
Dr Scott said, "This study suggests that bone marrow could be used as a therapeutic source of readily harvestable cells for the regeneration of nerve cells, with potential application to various neurodegenerative diseases and traumatic central nervous system damage". (ANI)
Washington April 30, 2004 11:40:07 AM IST
A preliminary study conducted at the University of Florida Shands Cancer Center, USA, suggests that transplanted adult bone-marrow cells could regenerate nerve cells in the brains of human stem-cell recipients.
The findings published in The Lancet, if confirmed in future research, could have implications for the treatment of neurodegenerative disorders such as Parkinson's disease.
Edward Scott and colleagues examined the brain tissue of three women who had received bone-marrow transplantation from male donors to help treat leukaemia.
The investigators found that donor cells containing a Y chromosome (ie, from a male origin) were present in all three women's brains up to 6 years after bone-marrow transplantation. All recipients had transgender brain tissue, and in the longest survivor three different types of brain tissue including neurons were found.
Dr Scott said, "This study suggests that bone marrow could be used as a therapeutic source of readily harvestable cells for the regeneration of nerve cells, with potential application to various neurodegenerative diseases and traumatic central nervous system damage". (ANI)
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